<International Circulation>: We know that omega-3 fatty acids have been around for about 30 years now. Can you tell us about some of the benefits of omega-3 fatty acids on cardiovascular disease prevention and treatment?
<International Circulation>: Speaking of supplements, do you think that the supplements really work in patients with hypertriglyceridemia?
《国际循环》:提到补充剂,您认为这种补充剂确实对高甘油三脂的患者有效吗?
Prof. Davidson: They certainly do work if you give enough of a dose. That is why we think that giving the free fatty acids can make it a lot more acceptable to give a high enough dose in patients that do have elevated triglycerides.
Davidson教授: 如果你给予足够的剂量它们确实有效。这也是为什么我们认为给予足够剂量的游离脂肪酸以降低患者体内的甘油三酯水平更容易为人们所接受。
<International Circulation>: Many people in this session are talking about various lipid profile parameters. In clinical practice, doctors usually only focus on LDLc levels. Even HDLc is not recommended as a treatment target. What is your opinion on this? Is there a big disparity between laboratory and clinical sciences regarding this issue?
《国际循环》:此次峰会上许多人都在谈论各种各样的血脂方面的参数。在临床实践中,医生通常只关注低密度脂蛋白水平,甚至高密度脂蛋白并没有被推荐为治疗的靶目标。对于这个问题您怎么看?实验室科学和临床科学对于这个问题是否有很大的差异呢?
Prof. Davidson: LDL and HDL are important parameters but when triglycerides are high all of that gets disturbed. In such instances LDLc does not really predict very well for heart disease. We think that the world is moving to an even higher triglyceride type of world and that although LDL cholesterol and HDL cholesterol are still important, triglycerides are really exacerbating both. We need to address this problem, otherwise we are going to see further decreases in cardiovascular health.
Davidson教授:低密度脂蛋白和高密度脂蛋白都是非常重要的参数,但是当甘油三酯非常高时,其他参数都会受影响。在这种情况下,低密度脂蛋白并不能真正很好地预防心脏疾病。我们认为甘油三酯正在逐渐升高并且成为主要的问题,尽管低密度脂蛋白和高密度脂蛋白仍然非常重要,甘油三酯可以使它们造成的危害进一步加重。我们需要解决这一问题,否则我们将会看到心血管健康的进一步降低。